fender 70′s reissue strat

My guitar amp send out a buzz/hum!?
well I play through a Fender Frontman
http://www.guitarcenter.com/Fender-Frontman-212R-100W-2×12-Guitar-Combo-Amp-104506076-i1323510.gc
and I play a 70′s reissue strat!
But when I go straight from my guitar to my amp I get very little or no hum….but I run though 4 pedals…… Its goes Wah>Distortion>Fuzz>Phaser>Amp
and thats when I get my really bad feedback mainly in my distortion and fuzz……but im told to change out my cables…..but should I?
Even If i run through my Hendrix pedal I still get feedback
Are you using digitech pedals? Because cheap pedals do that.
Change the line up of the pedals put the phase first and the wah last. Cables do make a difference but sounds like its a pedal.. You should plug one pedal in at a time guitar pedal amp for each pedal. This will narrow down the problem pedal if any.
I would say pick ups but you say its quite when there is no pedals. Good Luck
70′s Reissue Strat